The US security officials have warned labs against the use of Chinese test kits. [84] The same month, the United States Department of Commerce's Bureau of Industry and Security placed two BGI subsidiaries on its Entity List for assisting in alleged human rights abuses due to its genetic analysis work in Xinjiang. [72][73] In October 2015, BGI launched BGISEQ-500,[74] a larger desktop sequencing system, which received an approved registration as a medical device a year later by the CFDA. According to Reuters, the scientist is listed as affiliated with the PLA's Academy of Military Medical Science. BGI | Complete Birks Group Inc. stock news by MarketWatch. [15][16] By 2018, they were expanded with offices and laboratories in Seattle and San Jose in USA,[4] and London in the UK, as well were founded BGI Asia Pacific with offices in Hong Kong, Kobe (Japan), Bangkok (Thailand), Laos, Singapore, Brisbane (Australia) and many others. SYDNEY: BGI Group, the world's largest genomics company, has worked with China's military on research that ranges from mass testing for respiratory pathogens to brain science, a Reuters review of research, patent filings and other documents has found. [26], The BGI Group subsidiary, BGI Genomics, had made initial public offering in July 2017 at Shenzhen Stock Exchange, raising ¥547 million ($80.7 million), with company's first-day valuation set at over $1.15 billion. [6] The Shenzhen company says the low cost will be possible with an "extreme" DNA sequencing system it plans to offer that is capable of decoding the genomes of 100,000 people a year. It is done in collaboration with many institutes, universities and enterprises, including Biotechnology Research Institute of the Chinese Academy of Agricultural Sciences and the Tianjin Institute of Industrial Biotechnology of Chinese Academy of Sciences. [73] The China National GeneBank, opened by BGI and Chinese Government in September 2016,[75] has 150 instruments of the system. The Chinese company, the BGI Group, made the same offer to at least five other states, including New York and California, 60 Minutes has learned. Since the two reciprocal hybrids have different phenotypes, despite being genetically identical, it was expected that the epigenome might reveal the basis of such differences. Statement Regarding Misleading Media Reports about BGI; 11/17/2020. But BGI said Chen had no connection to the academy since 2012. In 2003, BGI Hangzhou and the Zhejiang University founded a new research institute, the James D. Watson Institute of Genome Sciences, Zhejiang University. Denmark Sets Example, Developing Digital Passports for Easy Traveling during Pandemic Times, Women Protesting For Alexei Navalny Being Made to Strip, Sexually Harassed by Russian Police -- Report, French Police Raid 81-Person Booze-Fueled Orgy for Violating COVID-19 Curfew. [46], An international project launched in 2002 and declared complete in 2009. [76] In 2017, BGI began offering WGS for $600. BGI Genomics, its main channel for commercialization, is a leading gene sequencing provider in China and went public in 2017. [52] An anonymous Chinese billionaire donated $10 million RMB (about US$1.4 million) to the project and his genome was sequenced at the beginning of the project. They also "co-developed a clinical whole exome diagnostic test offered through CHOP pathology since 2012". [7][8] After the project was completed, funding dried up, after which BGI moved to Hangzhou in exchange for funding from the Hangzhou Municipal Government. The focus of the paper was to experiment with the brains of monkeys who were suffering from altitude sickness. [57], Named the 1000 Plant Genomes Project (1KP), this was an international project launched in 2008 and declared complete in 2015. [65] The project aim was to significantly advance conservation research and was auspiciously announced for the Chinese year of the Tiger. The company has morphed from a research institute that decoded the DNA of pandas and rice plants into a company active in animal cloning, health testing, and contract research. Editor: James Boynton doi:10.1038/sdata.2019.22, "BGI Uses New Short-Read Algorithm to Assemble Panda Genome as Proof of Concept for Human Genome | BioInform | Informatics | GenomeWeb", "BGI Retools Complete Genomics Technology for Its New High-Throughput Benchtop Sequencer", "BGI Launches New Desktop Sequencer in China, Registers Larger Version With CFDA", "BGI Launches Desktop Sequencer in China; Plans to Register Platform With CFDA", "China National GeneBank Opens With Investments From BGI, Government", "BGI Launches New Sequencer as Customers Report Data From Earlier Instruments", "BGI's MGI Tech Launches Two New NGS Platforms", "MGI Introduces Groundbreaking Ultra-High-Throughput Sequencer, MGISEQ-T7", "BGI officially enters Urumqi High-tech Zone", "China expands DNA data grab in troubled western region", "China Uses DNA to Map Faces, With Help From the West", "Chinese coronavirus test maker agreed to build a Xinjiang gene bank", "Chinese biotech giant's U.S. subsidiary returns PPP loan after Axios story", "U.S. blacklists Chinese companies tied to Xinjiang gene bank project", "Commerce Department Adds Eleven Chinese Entities Implicated in Human Rights Abuses in Xinjiang to the Entity List", "China's genetics company BGI denies human rights violations of Uighurs", "Thousands of Swedes got false positive COVID-19 result due to test kit fault", "WHO Emergency Use Listing for In vitro diagnostics (IVDs) Detecting SARS-CoV-2", "Chinese Covid-19 test kit outstrips alternatives in Dutch study", "China's BGI defends COVID-19 test kit after Swedish criticism", "China's BGI gets Australian foothold through mass coronavirus test delivery", "Illumina Nears Win In Bid To Block BGI's DNA Product Sales", "BGI Sues Illumina for Antitrust Violation, Claims Firm Obtained Sequencing Patents Through Fraud", "China gene firm providing worldwide COVID tests worked with Chinese military", https://en.wikipedia.org/w/index.php?title=BGI_Group&oldid=1004333786, Biotechnology companies established in 1999, Genetics or genomics research institutions, Articles with a promotional tone from February 2020, Articles containing potentially dated statements from 2010, All articles containing potentially dated statements, Beijing articles missing geocoordinate data, Wikipedia articles with SUDOC identifiers, Wikipedia articles with WORLDCATID identifiers, Creative Commons Attribution-ShareAlike License, DNBseq™ Platform (next-generation sequencing platform), The NIFTY® Test (a non-invasive prenatal test), Sequenced the first ancient human's genome from the roughly 4,000-year-old permafrost-preserved hair of an extinct. In 2014, the BGI was reported to be producing 500 cloned pigs a year to test new medicines. [7][10], In 2010 BGI Shenzhen was certified as meeting the requirements of ISO9001:2008 standard for the design and provision of high-throughput sequencing services,[11] The same year BGI bought 128 Illumina HiSeq 2000 gene-sequencing machines,[4][7] which was backed by US$1.5 billion in "collaborative funds" over the next 10 years from the China Development Bank. China’s BGI says it can sequence a genome for just $100. Reuters reported that in terms of the US suspicion, the reviewed documents are neither contradictory nor supportive. BGI Group statement regarding subsidiaries being included on the US Bureau of Industry and Security (BIS) "Chinese entity list" We are puzzled by and greatly regret the decision of the Bureau of Industry and Security (BIS) under the U.S. Department of Commerce to include two BGI Group entities on the list of Chinese entities facing sanctions. But can it compete in the U.S.? Apr.28 -- Xu Xun, chief executive officer of BGI Group, discusses the Chinese medical technology firm's strategy to fight the Covid-19. [54][55] Other than publishing a new improved version of the popular Genome Wide Association Study tool PLINK,[56] the project was never completed and the lead researchers moved to the US to set up the company Genomic Prediction which provides advanced genetic testing for IVF. [46] With it were discovered genes and mutations associated with rare diseases, which was reported in more than 20 scientific publications. In terms of the COVID-19 test kit, BGI said it did not use the method jointly patented with PLA. In 2007 BGI's headquarters relocated to Shenzhen as "the first citizen-managed, non-profit research institution in China". [13][59] In 2018 it was announced that the 1KP project was being succeeded by the 10KP project to sequence 10,000 plant species to a high (chromosome level) quality. BGI Group, the world’s largest genomics company, has worked with China’s military on research that ranges from mass testing for respiratory pathogens to brain science, a Reuters review of research, patent filings and other documents has found.. China's BGI forecasts 700% jump in first-half profit due to COVID-19 test kit demand. [20], An international project launched in 1990 and declared complete in 2003. This page was last edited on 2 February 2021, at 02:50. BGI Group, based in Shenzhen, has grown quickly by selling genetic sequencing services to universities and health systems around the world and amassing a large DNA databank. The UK Minister said considering the emergence of thousands of variants,... Denmark Finance Minister revealed that the introduction of these digital... One of the detained women was forced to take off her bra and undress to... A total of 81 people were fined for violating the curfew and three people... BGI Group sold millions of COVID-19 test kits outside China, International Business Times, Singapore Edition, Where is BullHorn Lady? "BGI has worked on PLA projects seeking to make members of the ethnic Han Chinese majority less susceptible to altitude sickness—genetic research that would benefit soldiers in some border areas," found Reuters. [50][51] The first genome data was published in October 2007. Since China has the world's longest highland border, the purpose of such studies can be understood. Seven years ago, BGI began its bid to turn China into a DNA superpower by buying 128 of the world’s fastest sequencing machines---then the Illumina HiSeq 200. The final results were published in Nature in 2019. BGI COVID-19 RT-PCR Kit Receives Brazil ANVISA Registration; 09/23/2020. As COVID rates and the need for tests were spiking, BGI Group, the world's largest biotech firm - a global giant based in China - approached the state of Washington with an enticing offer. BGI Park, No.21 Hongan 3rd Street, Yantian District, Shenzhen 518083, China . The Chinese corporation contacted Democrat Jay Inslee, the governor of Washington, as well as New York, California, and other states, offering to build COVID-19 testing labs, according to 60 Minutes. [5][12][13] By the end of the year, they reportedly had a budget of $30 million. BGI Group is the largest biotech company in the world. [78], In 2019, it was reported that a BGI subsidiary, Forensic Genomics International, had created a WeChat-enabled database of genetic profiles of people across the country. [5] BGI did the genome sequencing for the deadly 2011 Germany E. coli O104:H4 outbreak in three days and released it under an open license. But when Reuters asked BGI regarding such research programs it said the collaboration with PLA and the Third Military Medical University was for "academic purposes only". Shenzhen Huada Gene Technology conducts business in China. It also revealed how the Asian county has moved to integrate the private technology firms into military-related research under the leadership of Xi Jinping. Plummeting COVID Cases Baffle Experts as Role of Vaccination Is Minimal, Who is Reverend David Fulton? National University of Defence Technology. [70], In 2010, the institute 500-node supercomputer processed 10 terabytes of raw sequencing data every 24 hours from its current 30 or so Genome Analyzers from Illumina. In response, BGI said that Peng and Liao Xiangke—who is the head of the NUDT's supercomputer program and a major general in the PLA—"were two collaborators of BGI for the project at the time for the purpose of academic exchange only. EXPOSED: BGI Group Providing Worldwide COVID-19 Tests A Front For Chinese Military January 30, 2021 BGI Group, the world’s largest genomics company which provided COVID-19 tests worldwide including India, has been exposed as a front for the Chinese military. [64], In 2010, BGI, Beijing University, Heilongjiang Manchurian tiger forestry zoo, Kunming Institute of Zoology, San Diego Zoo Institute for Conservation Research in California, and others announced they would sequence the Amur tiger, South China tiger, Bengal tiger, Asiatic lion, African lion, clouded leopard, snow leopard, and other felines. [33], SOAPdenovo is part of "Short Oligonucleotide Analysis Package" (SOAP), a suite of tools developed by BGI for de novo assembly of human-sized genomes, alignment, SNP detection, resequencing, indel finding, and structural variation analysis. The reported market value for BGI Genomics in July 2018 was around $5 billion, as is of another subsidiary, MGI Tech, specialized in developing and manufacturing technology, which IPO of a stake of about 20% for $1 billion is scheduled for 2019 in Hong Kong. [14] In 2010, BGI Americas was established with its main office in Cambridge, Massachusetts, USA, and BGI Europe was established in Copenhagen, Denmark. [68] This work was eventually completed presenting the genome assembly with a total length of 557 Mb. Reuters also revealed that four BGI researchers have been found to be affiliated with another military organization in China, the National University of Defence Technology (NUDT), which is on the US blacklist. For the biopharma industry investment, business development and competitive intelligence professionals who require information to support financing, partnering and licensing activities, BCIQ provides accurate information and context to support profitable and strategic decision making. Built for the Illumina sequencers' short reads, SOAPdenovo has been used to assemble multiple human genomes[29][30][31] (identifying an eight kilobase insertion not detected by mapping to the human reference genome[71]) and animals, like the giant panda. "BGI strongly rejects any accusations about links with the PLA, particularly in relation to our COVID-19 test kits," it added. [4][25] In May 2017, was announced formation of West Coast Innovation Center, co-located in Seattle and San Jose, on the first location planned to work on precision medicine and feature collaborations with University of Washington, the Allen Institute for Brain Science, the Bill & Melinda Gates Foundation, and Washington State University, while on the second's already existing laboratory with 100 employees to develop the next-generation sequencing technologies. [92][93] In response, BGI has filed patent infringement lawsuits against Illumina alleging violations of federal antitrust and California unfair competition laws. [4] In October 2017, MGI Tech, a subsidiary of BGI, launched two new sequencers MGISEQ-2000 and MGISEQ-200 (later renamed as DNBSEQ-G400 and DNBSEQ-G50),[77] while a year later DNBSEQ-T7. Sci Data 6, 190022 (2019). [28], Up until 2015, BGI had released BGISEQ-100, based on Thermo Fisher Scientific's Ion Torrent device, and BGISEQ-1000, based on similar technology by Complete Genomics, for both of which received an approval from the CFDA for a NIFTY (Non-invasive Fetal Trisomy Test) prenatal test. The Reuters report pointed out a research paper which was authored by BGI founders Yang Huanming and Wang Jian in collaboration with PLA's Key Laboratory of High-Altitude Medicine and the Third Military Medical University. [53], The project was started on 1 August 2009, with the mission to sequence 10,000 microbes within 3 years. The three selected genomes are those of two polar animals: the polar bear and emperor penguin, and one altiplano animal: the Tibetan antelope. [17][18], In 2011 BGI reported it employed 4,000 scientists and technicians,[2] and had a $192 million in revenue. BGI Group, based in Shenzhen, has grown quickly by selling genetic sequencing services to universities and health systems around the world and amassing a large DNA databank. [5] In 2008, BGI-Shenzhen was officially recognized as a non-profit organization by the Shenzhen government. Founded in 1999, BGI Group combines academic research and commercial development of the life sciences. As per the report, Bill Evanina, the country's top counterintelligence officer, believes that the Chinese are trying to collect DNA to control the world's biodata. [53], A project called the Cognitive Genomics project focused on the research of the genetic basis of intelligence was announced in August 2012. But intelligence officials in the US issued warnings not to share health data with BGI. Clinical Lab Partnership Program Provides Ready Supplies and Reliable Support for COVID-19 Testing But it added that the documents showed a much deeper link between BGI and the Chinese military than what was known. The review, of more than 40 publicly available documents and research papers in Chinese and … But according to a newly published report, it was found that the Shenzhen-based firm has deep ties to the People's Liberation Army (PLA) and that became a concern of the US intelligence officials. [19] Since 2012, it has started to commercialize its services, having investments from China Life Insurance Company, Citic's Goldstone Investment, Jack Ma's Yunfeng Capital, and SoftBank China Capital. It includes sequencing industrial, agricultural, medical microorganism and many others. This week another report from 60 Minutes revealed that the Chinese firm offered to build COVID-19 labs in at least six American states. It reportedly received more than 500 orders for the system and run over 112,000 tests until late 2016. The analysis of the documents revealed BGI's links to the PLA that included research with the country's top military supercomputing experts. [20] That year they also launched their own scientific journal, GigaScience,[21] partnering with BioMed Central to publish data-heavy life science papers. BGI, currently known as the BGI Group, formerly known as the Beijing Genomics Institute, is a Chinese genome sequencing company, headquartered in Shenzhen, Guangdong, China. [24] That year it bought Complete Genomics of Mountain View, California, a major supplier of DNA sequencing technology, for US$118 million. BGI Group announced at the AGBT conference in February 2020 that it will make genome sequencing cheaper, breaking the $100 barrier for the first time. BELGRADE, April 8 (Xinhua) -- China's biotech company BGI group will open two COVID-19 testing labs in Serbia to help fight the COVID-19 pandemic, according to an agreement it signed with the Serbian government Wednesday. UK Minister Says There Are 4,000 Virus Variants Causing Covid-19; Is the World Ready? [61] The Tibetan antelope genome was published in 2013,[62] the polar bear in 2014,[63] and the Emperor and Adelie penguin genomes in 2014. In this particular research, experts looked at the effects of rapid ascent to high altitude on the bodies of "young, healthy men.". [67], A jointly funded project announced on 19 March 2010, BGI announced it would collaborate with Sidney K. Pierce of University of South Florida and Charles Delwiche of the University of Maryland at College Park to sequence the genomes of the sea slug, Elysia chlorotica, and its algal food Vaucheria litorea. The sea slug uses genes from the algae to synthesize chlorophyll, the first interspecies of gene transfer discovered. BGI also stated that it uses the supercomputer located in the National Supercomputer Center in Guangzhou on a commercial basis and other supercomputing platforms to speed up the research process. BGI, China’s leading genetics company, enlisted a foundation tied to a former U.S. president and used a company linked to the United Arab Emirates’ top spy to promote its efforts. Sequencing their genomes could elucidate the mechanism of that transfer. In 2010, the company created China's first cloned pig. The Group consists of divisions including BGI Genomics, which focuses on diagnostic tests and services, and MGI, which develops and manufactures advanced equipment such as sequencers, lab automation robots, and imaging. NUDT runs under the supervision of the Central Military Commission, the top-level body that directs the Chinese military and is headed by Xi Jinping. The annual budget for the computer center was US$9 million. In 2003 BGI decoded the SARS virus genome and created a kit for detection of the virus. [46], An international project launched in 2008. American physicist Stephen Hsu joined as a scientific adviser and was one of the project's leaders. [1][27] In 2018, the BGI was reportedly 85.3% owned by Wang Jian, and the group owns 42.4% of its main unit BGI Genomics. [72] In November 2016, BGI launched BGISEQ-50, a miniature version of desktop sequencer. [54] It was done on 2,200 samples mostly from the United States,[46] out of which 1,600 were of individuals who participated in the Study of Mathematically Precocious Youth and reportedly have IQs over 160, collected by American psychologist and geneticist Robert Plomin. But BGI has denied such allegations. [66] The liger and tigon projects were never carried out, but results were reported in 2013 for the genomes of the Amur tiger, the white Bengal tiger, African lion, white African lion and snow leopard. In 2010, BGI received a $1.5 billion loan from the state-run China Development Bank, some of which it used to buy 128 sequencing machines from an American firm, San Diego-based Illumina Inc. [50][51], An international project to establish a detailed catalogue of human genetic variation launched in 2008 and declared complete in 2015. The algorithm, called SOAPdenovo, can assemble a genome in two days and has been used to assemble an array of plant and animal genomes. "BGI Group, the world’s largest genomics company, has worked with China’s military on research that ranges from mass testing for respiratory pathogens to brain science, a Reuters review of research, patent filings and other documents has found. [95], Three Extreme-Environment Animal Genomes Project, Allegations of genetic surveillance in Xinjiang, Allegations of faulty COVID-19 testing kit, Learn how and when to remove this template message, James D. Watson Institute of Genome Sciences, Zhejiang University, National University of Defense Technology, "A Chinese Genome Giant Sets Its Sights on the Ultimate Sequencer", https://www.technologyreview.com/s/615289/china-bgi-100-dollar-genome/, An Interview with a Leader in Genomics — Beijing Genomics Institute, "Next Generation of High-Throughput Sequencing Service of BGI Received the ISO9001 Certification", "BGI to Receive $1.5B in 'Collaborative Funds' Over 10 Years from China Development Bank | In Sequence | Sequencing | GenomeWeb", "Chinese institute makes bold sequencing play", "Genome Giant Seeks $1 Billion for Equipment Unit for Potential IPO", "Large and linked in scientific publishing the launch of big data journal GigaScience", "DNA Sequencing Caught in Deluge of Data", "China embraces precision medicine on a massive scale", "A Chinese company unveils a powerful new sequencer. The Watson Institute was intended to become a major center for research and education in East Asia modeled after the Cold Spring Harbor Laboratory in the US. BGI's Wang was involved in another study from 2017 that was published in collaboration with a PLA research center in Xinjiang. Super-cheap DNA sequencing could boost cancer screening, prenatal tests, and research into population genetics. Fact-Check: Did Trump Illegally Use the President's Seal on Letter Resigning from SAG-AFTRA? Chinese genome sequencing company BGI Group, which was previously known as the Beijing Genomics Institute, has sold millions of COVID-19 test kits outside mainland China, including the US, Europe and Australia. According to Elsa Kania, who is an adjunct senior fellow at the Center for a New American Security think tank, the Chinese military has pushed research on brain science, the creation of artificial DNA and gene editing that could have an application in the future bioweapons. [94], In January 2021, Reuters reported that BGI has worked with the People's Liberation Army and affiliated institutions such as the National University of Defense Technology on efforts to enhance soldiers' strength and other projects. Chen is listed as an inventor on the patent documents. Chinese genome sequencing company BGI Group, which was previously known as the Beijing Genomics Institute, has sold millions of COVID-19 test kits outside mainland China, including the US, Europe and Australia. Wang Jian, Yu Jun, Yang Huanming and Liu Siqi created BGI in September 1999,[5] in Beijing, China as a non-governmental independent research institute in order to participate in the Human Genome Project as China's representative. [2][3], It was formed in 1999 to participate in the Human Genome Project as a genetics research center. "One researcher, Peng Shaoliang, was instrumental in developing software to speed up BGI's sequencing of human genomes using supercomputing developed by NUDT," reported Reuters. The research paper, published in 2020, said that the study was funded as one of the "key projects of military science and technology" by the PLA. In January 2018, BGI Genomics CEO, Yin Ye, stated they sequenced over 10,000 WGS samples, with additional 20,000 being sequenced by their BGISEQ-500 platform, about 70% of animals and plants until now were sequenced by the company and their partners, as well worked on "over 10 million clinical samples, including running 2.8 million noninvasive prenatal tests, 2.6 million human papillomavirus tests, 1.53 million hearing impairment tests, just over half a million newborn screening tests, and around 25,000 rare disease tests". [4] It also sequences genomes of other animals, plants and microorganisms.[5]. [60], In 2009 BGI-Shenzhen announced the launch of three genome projects that focus on animals living in extreme environments. [79][80][81][82][83] In July 2020, it was reported that BGI returned a Paycheck Protection Program loan following media scrutiny. [85][86] BGI responded to the listing stating they "do not condone and would never be involved in any human-rights abuses" and stating that they were puzzled by the decision as the "subsidiary mentioned was established in November 2016 and has not carried out actual business"[87], On August 25, 2020, Reuters reported that about 3,700 people in Sweden were told in error that they had the coronavirus due to a fault in a COVID-19 testing kit from BGI Genomics. [5][19] In the same year, the BGI was roughly valued at $820 million. [22] In 2013 BGI reported it had relationships with 17 out of the top 20 global pharmaceutical companies,[5][23] and advertised that it provided commercial science, health, agricultural, and informatics services to global pharmaceutical companies. SYDNEY: BGI Group, the world's largest genomics company, has worked with China's military on research that ranges from mass testing for respiratory pathogens to. BGI has worked on PLA projects seeking to make members of the ethnic Han Chinese majority less susceptible to altitude sickness, Reuters found, genetic It created China… It was announced at the time that BGI would also sequence the genomes and epigenomes of a liger and tigon. info@bgi.com [4] In May 2018, was reached an agreement with Mount Sinai Hospital (Toronto), Canada, for first installation of BGISEQ platforms in North America. 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